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TASP0434299

Chemical Structure : TASP0434299

CAS No.: 1520893-08-6

TASP0434299 (TASP 0434299)

Catalog No.: PC-61507Not For Human Use, Lab Use Only.

A radioligand candidate for arginine vasopressin 1B (V1B) receptor that exhibits high binding affinities for human and rat V1B receptors with IC50 of 0.526 and 0.641 nM, respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A radioligand candidate for arginine vasopressin 1B (V1B) receptor that exhibits high binding affinities for human and rat V1B receptors with IC50 of 0.526 and 0.641 nM, respectively; shows no apparent binding affinities for other molecules at 1 uM.

Physicochemical Properties

M.Wt 509.607
Formula C27H35N5O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-tert-butyl-2-[2-(3-methoxyphenyl)-6-[3-(morpholin-4-yl)propoxy]-4-oxopyrido[2,3-d]pyrimidin-3(4H)-yl]acetamide

References

1. Koga K, et al. J Pharmacol Exp Ther. 2016 Jun;357(3):495-508.

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