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TCMCB07

Chemical Structure : TCMCB07

CAS No.:

TCMCB07

Catalog No.: PC-49060Not For Human Use, Lab Use Only.

TCMCB07 is a synthetic, cyclic nonapeptide peptide antagonist of the melanocortin-4 receptor (MC4R), ameliorates cancer- and chronic kidney disease-associated cachexia.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

TCMCB07 is a synthetic, cyclic nonapeptide peptide antagonist of the melanocortin-4 receptor (MC4R), ameliorates cancer- and chronic kidney disease-associated cachexia.

Physicochemical Properties

M.Wt
Formula
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Ac‐Nle‐c[Asp‐Pro‐dNal2′‐Arg‐Trp‐Lys]‐dVal‐dPro‐NH2

References

1. Zhu X, et al. J Clin Invest. 2020 Sep 1;130(9):4921-4934.

2. Hu Y, et al. J Cachexia Sarcopenia Muscle. 2020 Dec;11(6):1677-1687.

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