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TCS PIM-1 1

Chemical Structure : TCS PIM-1 1

CAS No.: 491871-58-0

TCS PIM-1 1 (SC 204330;TCS PIM 1-1)

Catalog No.: PC-45414Not For Human Use, Lab Use Only.

TCS PIM-1 1 (SC 204330) is a potent, selective, ATP-competitive Pim-1 kinase inhibitor with IC50 of 50 nM; displays >400-fold selectivity over Pim-2 and MEK1/2.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

TCS PIM-1 1 (SC 204330) is a potent, selective, ATP-competitive Pim-1 kinase inhibitor with IC50 of 50 nM; displays >400-fold selectivity over Pim-2 and MEK1/2.

Physicochemical Properties

M.Wt 367.1961
Formula C18H11BrN2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 52 mg/mL

Chemical Name/SMILES

3-Pyridinecarbonitrile, 6-(5-bromo-2-hydroxyphenyl)-1,2-dihydro-2-oxo-4-phenyl-

References

1. Cheney IW, et al. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1679-83.

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