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Chemical Structure : TD-1
Catalog No.: PC-62380Not For Human Use, Lab Use Only.
Hemoglobin modulator TD-1 (TD-1) is a novel allosteric effector of hemoglobin that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling.
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Hemoglobin modulator TD-1 (TD-1) is a novel allosteric effector of hemoglobin that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling; increases the oxygen affinity of sickle hemoglobin and inhibits in vitro hypoxia-induced sickling of red blood cells in patients with sickle cell disease without causing hemolysis; a novel lead molecule for the treatment of patients with sickle cell disease.
| M.Wt | 468.506 | |
| Formula | C20H16N6O4S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Nakagawa A, et al. ACS Chem Biol. 2014 Oct 17;9(10):2318-25.
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