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TDI-11861

Chemical Structure : TDI-11861

CAS No.: 2857049-72-8

TDI-11861 (TDI 11861)

Catalog No.: PC-49437Not For Human Use, Lab Use Only.

TDI-11861 a potent, selective second-generation soluble adenylyl cyclase (sAC, ADCY10) inhibitor with cellular IC50 of 5.5 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

TDI-11861 a potent, selective second-generation soluble adenylyl cyclase (sAC, ADCY10) inhibitor with cellular IC50 of 5.5 nM.

Physicochemical Properties

M.Wt 494.928
Formula C22H25ClF2N6O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-(4-(2-(2-((3-(2-amino-6-chloropyrimidin-4-yl)-1-(difluoromethyl)-1H-pyrazol-4-yl)methyl)phenoxy)ethyl)morpholin-3-yl)methanol

References

1. Michael Miller, et al. Journal of Medicinal Chemistry, November 8, 2022.

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