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TDI-6118

Chemical Structure : TDI-6118

CAS No.:

TDI-6118

Catalog No.: PC-72365Not For Human Use, Lab Use Only.

TDI-6118 is a potent, selective brain-penetrant EZH2 inhibitor with IC50 of 14 nM, inhibits cellular H3K27me with IC50 of 580 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

TDI-6118 is a potent, selective brain-penetrant EZH2 inhibitor with IC50 of 14 nM, inhibits cellular H3K27me with IC50 of 580 nM.

Physicochemical Properties

M.Wt 460.355
Formula C23H23Cl2N3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Month
Shipping
Solubility

Chemical Name/SMILES

References

1. Rui Liang, et al. ACS Med Chem Lett. 2022 Feb 10;13(3):377-387.

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