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TH-3021

Chemical Structure : TH-3021

CAS No.: 700856-05-9

TH-3021 (SN336384)

Catalog No.: PC-72285Not For Human Use, Lab Use Only.

TH-3021 (SN336384) is a potent and specific inhibitor of AKR1C3 with IC50 of 110 nM in isolated enzyme assays and 18 nM in cellular assays, displays no inhibitory action against AKR1C1/1C2/1C4 (IC50>30 uM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

TH-3021 (SN336384) is a potent and specific inhibitor of AKR1C3 with IC50 of 110 nM in isolated enzyme assays and 18 nM in cellular assays, displays no inhibitory action against AKR1C1/1C2/1C4 (IC50>30 uM).

Physicochemical Properties

M.Wt 309.794
Formula C15H20ClN3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Month
Shipping
Solubility

Chemical Name/SMILES

References

1. Jack U Flanagan, et al. Bioorg Med Chem. 2014 Feb 1;22(3):967-77.

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