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Chemical Structure : TJ191
Catalog No.: PC-63231Not For Human Use, Lab Use Only.
TJ191 is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells (MOLT-3 IC50=0.26 uM).
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TJ191 is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells (MOLT-3 IC50=0.26 uM); selectively targets certain cancer cells without affecting the proliferation of other cancer cells or normal fibroblasts or immune cells (over 600-fold selectivity), TβRIII acts as a predictive marker for TJ191 sensitivity in malignant T-cells.
| M.Wt | 255.376 | |
| Formula | C13H21NO2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. El-Gazzar A, et al. Oncotarget. 2017 Dec 15;9(5):6259-6269.
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