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Chemical Structure : Tezampanel
Catalog No.: PC-61713Not For Human Use, Lab Use Only.
Tezampanel (LY 293558, NGX 424) is a competitive antagonist of the AMPA and kainate receptors with selectivity for the GluR5 subtype of the kainate receptor.
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Tezampanel (LY 293558, NGX 424) is a competitive antagonist of the AMPA and kainate receptors with selectivity for the GluR5 subtype of the kainate receptor; has neuroprotective and anticonvulsant properties, also has anxiolytic effects in animal studies.
Migraine
Discontinued
| M.Wt | 279.344 | |
| Formula | C13H21N5O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ornstein PL, et al. J Med Chem. 1993 Jul 9;36(14):2046-8.
2. LeBlanc MH, et al. Stroke. 1995 Oct;26(10):1908-14; discussion 1914-5.
3. Benvenga MJ, et al. J Pharmacol Exp Ther. 1995 Oct;275(1):164-70.
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