Chemical Structure : Tizanidine
CAS No.: 51322-75-9
Catalog No.: PC-27360Not For Human Use, Lab Use Only.
Tizanidine is a skeletal muscle relaxant and an orally effective central α2-adrenoceptor agonist (IC50=6 nM), exerts muscle relaxation effects by inhibiting the release of excitatory amino acids (glutamate and aspartate) from the presynaptic terminals of spinal cord interneurons, also inhibits the proliferation, migration, and invasion of lung cancer cells.
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Tizanidine is a skeletal muscle relaxant and an orally effective central α2-adrenoceptor agonist (IC50=6 nM), exerts muscle relaxation effects by inhibiting the release of excitatory amino acids (glutamate and aspartate) from the presynaptic terminals of spinal cord interneurons, also inhibits the proliferation, migration, and invasion of lung cancer cells.
| M.Wt | 253.71 | |
| Formula | C9H8ClN5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)benzo[c][1,2,5]thiadiazol-4-amine |
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1. Kamen L, et al. Curr Med Res Opin. 2008 Feb;24(2):425-39.
2. Granfors, M. T., et al. Br J Clin Pharmacol。 2004 Mar;57(3):349-53.

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