Catalog No.: PC-26777Not For Human Use, Lab Use Only.
Trazodone (AF-1161) is an antidepressant that inhibits reuptake of serotonin, causes adrenoreceptor subsensitivity, acts as a 5HT2a receptor antagonist and induces significant changes in 5-HT presynaptic receptor adrenoreceptors, also significantly blocks histamine (H1) and alpha1-adrenergic receptors.
Trazodone (AF-1161) is an antidepressant that inhibits reuptake of serotonin, causes adrenoreceptor subsensitivity, acts as a 5HT2a receptor antagonist and induces significant changes in 5-HT presynaptic receptor adrenoreceptors, also significantly blocks histamine (H1) and alpha1-adrenergic receptors.
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2. Ghanbari, R., et al., (2010). Sustained administration of trazodone enhances serotonergic neurotransmission: in vivo electrophysiological study in the rat brain. The Journal of pharmacology and experimental therapeutics, 335(1), 197–206.
