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Chemical Structure : UCPH-101
CAS No.: 1118460-77-7
Catalog No.: PC-62148Not For Human Use, Lab Use Only.
UCPH-101 is a selective non-substrate inhibitor of EAAT1 (Excitatory amino acid transporter 1) with IC50 of 660 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $258 | In stock | |
| 25 mg | $458 | In stock | |
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| 250 mg | Get quote | ||
| 1 g | Get quote |
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UCPH-101 is a selective non-substrate inhibitor of EAAT1 (Excitatory amino acid transporter 1) with IC50 of 660 nM.
UCPH-101 dispalys >50-fold selectivity over EAAT2 and EAAT3, and has no significant inhibition at EAAT4 or EAAT5.
| M.Wt | 422.48 | |
| Formula | C27H22N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(1-naphthalenyl)-5-oxo-4H-1-benzopyran-3-carbonitrile |
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1. Canul-Tec JC, et al. Nature. 2017 Apr 27;544(7651):446-451.
2. Jensen AA, et al. J Med Chem. 2009 Feb 26;52(4):912-5.
3. Abrahamsen B, et al. J Neurosci. 2013 Jan 16;33(3):1068-87.
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