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Chemical Structure : UMB-32
Catalog No.: PC-60389Not For Human Use, Lab Use Only.
UMB-32 is a potent, selective inhibitor of BRD4 with Kd of 550 nM, cellular IC50 of 724 nM.
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UMB-32 is a potent, selective inhibitor of BRD4 with Kd of 550 nM, cellular IC50 of 724 nM.
UMB-32 also potently binds to the TAF1 (560 nM) and TAF1L (1.3 uM) bromodomains.
UMB-32 significantly induces HIV-1 reactivation.
| M.Wt | 361.4 | |
| Formula | C21H23N5O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. McKeown MR, et al. J Med Chem. 2014 Nov 13;57(21):9019-27.
2. Huang H, et al. Front Microbiol. 2017 Jun 7;8:1035.
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