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Chemical Structure : UNC-BE4-017
Catalog No.: PC-21869Not For Human Use, Lab Use Only.
UNC-BE4-017 is a selective STK3 small-molecule inhibitor, also potently inhibits JAK1, JAK2, and JAK3, but not other kinases in a panel of 48 kinases.
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UNC-BE4-017 is a selective STK3 small-molecule inhibitor, also potently inhibits JAK1, JAK2, and JAK3, but not other kinases in a panel of 48 kinases.
UNC-BE4-017 shows affinity to STK3 in live cells in the STK3-NanoBRET assay with IC50 of 7.6 uM.
UNC-BE4-017 inhibits prostate cancer (PC) cell proliferation.
| M.Wt | 286.38 | |
| Formula | C16H22N4O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Amelia U Schirmer, et al. Mol Ther. 2022 Jan 5;30(1):485-500.
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