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Chemical Structure : UNC-CA157
Catalog No.: PC-49413Not For Human Use, Lab Use Only.
UNC-CA157 is a selective small molecule inhibitor of the archetypal UbiB member COQ8A with IC50 of 580 nM, shows clear preference for COQ8A over COQ8B.
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UNC-CA157 is a selective small molecule inhibitor of the archetypal UbiB member COQ8A with IC50 of 580 nM, shows clear preference for COQ8A over COQ8B.
UNC-CA157 (20 uM) decreases de novo CoQ production in COQ8BKO HAP1 cells.
| M.Wt | 335.363 | |
| Formula | C19H17N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Nathan H Murray, et al. Nat Chem Biol. 2022 Oct 27. doi: 10.1038/s41589-022-01168-3.
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