You are here:Home-Chemical Inhibitors & Agonists-GPCR-Histamine Receptor-UR-PI376
UR-PI376

Chemical Structure : UR-PI376

CAS No.: 1192559-94-6

UR-PI376 (UR PI376)

Catalog No.: PC-63422Not For Human Use, Lab Use Only.

UR-PI376 is a potent, selective histamine H4 receptor (hH4R) agonist with pEC50 of 7.47, shows negligible hH1R and hH2R activities and significant selectivity over the hH3R..

Packing Price Stock Quantity
10 mg Get quote
25 mg Get quote
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    UR-PI376 is a potent, selective histamine H4 receptor (hH4R) agonist with pEC50 of 7.47, shows negligible hH1R and hH2R activities and significant selectivity over the hH3R.

    Physicochemical Properties

    M.Wt 342.465
    Formula C17H22N6S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-cyano-1-[4-(1H-imidazol-4-yl)butyl]-3-[(2-phenylthio)ethyl]guanidine

    References

    1. Igel P, et al. J Med Chem. 2009 Oct 22;52(20):6297-313.

    2. Reher TM, et al. Biochem Pharmacol. 2012 Jul 15;84(2):192-203.

    3. Gschwandtner M, et al. Br J Pharmacol. 2013 Sep;170(1):136-43.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: