USP47-IN-1

Chemical Structure : USP47-IN-1

Catalog No.: PC-28629Not For Human Use, Lab Use Only.

USP47-IN-1 (Compound 3) is a specific small molecule inhibitor of deubiquitinating enzyme USP47 with IC50 of 0.46 uM, shows 10-fold selectivity over USP7, covalently binds at the thumb-palm cleft and sterically blocks Ub binding.

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Biological Activity

Physicochemical Properties

M.Wt	292.33
Formula	C19H16O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	O=C(C1(C(C2=CC=CC=C2)O1)CC3)C3(O4)C4C5=CC=CC=C5

References

1. Jones HBL, et al. NPJ Drug Discov. 2026 Oct 26;3(1):52.

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USP47-IN-1

Biological Activity

Physicochemical Properties

References

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