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Chemical Structure : VAL-083
CAS No.: 23261-20-3
Catalog No.: PC-20967Not For Human Use, Lab Use Only.
VAL-083 (Dianhydrodulcitol) is a small alkylating molecule that induces interstrand DNA crosslinking, induces persistent DNA double-strand breaks (DSB) and cell-cycle arrest in a p53-dependent or p53-independent manner.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $498 | In stock | |
| 100 mg | Get quote |
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VAL-083 (Dianhydrodulcitol) is a small alkylating molecule that induces interstrand DNA crosslinking, induces persistent DNA double-strand breaks (DSB) and cell-cycle arrest in a p53-dependent or p53-independent manner.
| M.Wt | 146.14 | |
| Formula | C6H10O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
O[C@H]([C@H](O)[C@@]1(CO1)[H])[C@]2(CO2)[H] |
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1. Jiménez-Alcázar M, et al. Mol Cancer Ther. 2021 Jun;20(6):1029-1038.
2. Golebiewska A, et al. Acta Neuropathol. 2020 Dec;140(6):919-949.
3. Nemeth L, et al. Cancer Chemother Rep 1972;56:593–602.
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