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Chemical Structure : VGSC blocker 4
Catalog No.: PC-35118Not For Human Use, Lab Use Only.
VGSC blocker 4 is a potent, small molecule blocker of neonatal isoform of the VGSC subtype, Nav1.5 (nNav1.5), blocks INa peak currents 25% at 1 uM.
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VGSC blocker 4 is a potent, small molecule blocker of neonatal isoform of the VGSC subtype, Nav1.5 (nNav1.5), blocks INa peak currents 25% at 1 uM; inhibits cell invasion 28% at 1 uM in human breast cancer cell line MDA-MB-231, without affecting the cell viability..
| M.Wt | 292.442 | |
| Formula | C18H29FN2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Dutta S, et al. Bioorg Med Chem. 2018 May 15;26(9):2428-2436.
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