VU0521426 | Kv3.1 channel inhibitor | Probechem Biochemicals

Chemical Structure : VU0521426

VU0521426 (VU426)

Catalog No.: PC-26855Not For Human Use, Lab Use Only.

VU0521426 (VU426) is a potent, selective Kv3.1 channel inhibitor with IC50 of 4.3 uM, suppresses Kv3.1 activity413through a state-dependent mechanism consistent with stabilization of non-conducting channel states.

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Biological Activity

Physicochemical Properties

M.Wt	421.96
Formula	C19H20ClN3O2S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-((5-chlorothiophen-2-yl)sulfonyl)-4-((2-phenyl-1H-imidazol-1-yl)methyl)piperidine

References

1. Rahul U Chandrappa, et al. Am J Physiol Cell Physiol. 2026 May 15.

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VU0521426 (VU426)

Biological Activity

Physicochemical Properties

References

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