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VX-853

Chemical Structure : VX-853

CAS No.: 179033-51-3

VX-853 (Timcodar, VX853)

Catalog No.: PC-21827Not For Human Use, Lab Use Only.

Timcodar (VX-853) is small molecule modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1), directly blockes EtBr efflux in S. aureus.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Timcodar (VX-853) is small molecule modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1), directly blockes EtBr efflux in S. aureus.

Physicochemical Properties

M.Wt 749.31
Formula C43H45ClN4O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S)-N-benzyl-3-(4-chlorophenyl)-N-(1,5-dipyridin-4-ylpentan-3-yl)-2-[methyl-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]amino]propanamide

References

1. Mullin S, et al. Antimicrob Agents Chemother. 2004 Nov;48(11):4171-6.

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