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Vitacoxib

Chemical Structure : Vitacoxib

CAS No.: 1374128-90-1

Vitacoxib

Catalog No.: PC-61415Not For Human Use, Lab Use Only.

A potent, selective COX-2 inhibitor with IC50 of 0.34 ug/mL, >50-fold selectivity over COX-1 (IC50=19.4 ug/mL).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A potent, selective COX-2 inhibitor with IC50 of 0.34 ug/mL, >50-fold selectivity over COX-1 (IC50=19.4 ug/mL); a novel nonsteroidal anti-inflammatory drugs for veterinary use.

Physicochemical Properties

M.Wt 347.82
Formula C16H14ClN3O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(4-chloro-5-(p-tolyl)-1H-imidazol-1-yl)-5-(methylsulfonyl)pyridine

References

1. Wang J, et al. Regul Toxicol Pharmacol. 2017 Jun;86:49-58.

2. Wang J, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 1;1061-1062:270-274.

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