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Chemical Structure : Vutiglabridin
Catalog No.: PC-73455Not For Human Use, Lab Use Only.
Vutiglabridin (HSG4112) is a synthetic structural analog of glabridin and insulin sensitizer, novel anti-obesity agent.
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Vutiglabridin (HSG4112) is a synthetic structural analog of glabridin and insulin sensitizer, novel anti-obesity agent.
HSG4112 dose-dependently reduces body weight and normalizes obesity-related parameters in HFD-induced obese mice orally administered with 10, 30, or 100 mg/kg dose for 6 weeks.
HSG4112 enhances energy expenditure in HFD-induced obese mice.
HSG4112 regulates metabolic gene expression toward increased energy expenditure in liver and muscles.
HSG4112 ameliorates fatty liver in HFD-induced obese mice orally administered with 100 mg/kg dose for 6 weeks
| M.Wt | 354.446 | |
| Formula | C22H26O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Choi LS, et al. Int J Obes (Lond). 2021 Jan;45(1):130-142.
2. Bae IY, et al. Pharmaceutics. 2020 Feb 3;12(2):127.
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