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WEE1/CK1α degrader 2

Chemical Structure : WEE1/CK1α degrader 2

CAS No.:

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WEE1/CK1α degrader 2

Catalog No.: PC-22393Not For Human Use, Lab Use Only.

WEE1/CK1α degrader 2 is a highly potent WEE1/CK1α molecular glue degrader with DC50 of 1.6/1.5 nM, respectively, Emax >98%.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

WEE1/CK1α degrader 2 is a highly potent WEE1/CK1α molecular glue degrader with DC50 of 1.6/1.5 nM, respectively, Emax >98%.

Physicochemical Properties

M.Wt 537.62
Formula C31H31N5O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(5-(2-(adamantan-1-ylamino)imidazo[1,2-a]pyridine-3-carbonyl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

References

1. Razumkov H, et al. bioRxiv [Preprint]. 2024 May 5:2024.05.04.592550.

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