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Chemical Structure : WK-298
Catalog No.: PC-60436Not For Human Use, Lab Use Only.
WK-298 (Novartis 101) is a potent small molecule inhibitor that binds and disrupts the MDM2/MDMX-p53 interaction with IC50 of 0.19 uM and 19.7 uM, respectively.
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WK-298 (Novartis 101) is a potent small molecule inhibitor that binds and disrupts the MDM2/MDMX-p53 interaction with IC50 of 0.19 uM and 19.7 uM, respectively.
| M.Wt | 629.63 | |
| Formula | C35H38Cl2N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Popowicz GM, et al. Cell Cycle. 2010 Mar 15;9(6):1104-11.
2. Lemos A, et al. Med Res Rev. 2016 Sep;36(5):789-844.
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