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Wee1 Inhibitor II

Chemical Structure : Wee1 Inhibitor II

CAS No.: 622855-50-9

Wee1 Inhibitor II

Catalog No.: PC-72319Not For Human Use, Lab Use Only.

Wee1 Inhibitor II is a potent, selective, ATP-binding site-targeting inhibitor of Wee1 with IC50 of 59 nM, 590-fold selectivity over the related checkpoint kinase Chk1 (IC50=35 uM).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Wee1 Inhibitor II is a potent, selective, ATP-binding site-targeting inhibitor of Wee1 with IC50 of 59 nM, 590-fold selectivity over the related checkpoint kinase Chk1 (IC50=35 uM).

Physicochemical Properties

M.Wt 418.877
Formula C24H19ClN2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Month
Shipping
Solubility

Chemical Name/SMILES

References

1. Palmer, B.D., et al. 2006. J. Med. Chem. 49: 4896-4911.

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