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YPC-22026

Chemical Structure : YPC-22026

CAS No.: 1964457-41-7

YPC-22026 (YPC22026)

Catalog No.: PC-62589Not For Human Use, Lab Use Only.

YPC-22026, a metabolically stable derivative of YPC-21661, is a novel small molecule inhibitor of the transcription factor Zinc-finger protein 143 (ZNF143), inhibits the binding of ZNF143 to DNA.

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    Biological Activity

    YPC-22026, a metabolically stable derivative of YPC-21661, is a novel small molecule inhibitor of the transcription factor Zinc-finger protein 143 (ZNF143), inhibits the binding of ZNF143 to DNA.
    YPC-22026 induces tumor regression accompanied by the suppression of ZNF143-regulated genes in a mouse xenograft model.

    Physicochemical Properties

    M.Wt 331.254
    Formula C16H8F3N3O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-(pyridine-3-ylethynyl)-5-(2-(trifluoromethoxy)phenyl)-1,3,4-oxadiazole

    References

    1. Haibara H, et al. Cancer Sci. 2017 May;108(5):1042-1048.

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