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Chemical Structure : ZINC 39395747
Catalog No.: PC-60880Not For Human Use, Lab Use Only.
ZINC 39395747 is a novel potent derivative of propylthiouracil that functions as a cell-active inhibitor of cytochrome b5 reductase 3 (CYB5R3) with IC50 of 9.14 uM.
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ZINC 39395747 is a novel potent derivative of propylthiouracil that functions as a cell-active inhibitor of cytochrome b5 reductase 3 (CYB5R3) with IC50 of 9.14 uM.
ZINC 39395747 significantly increases NO bioavailability in renal vascular cells, augments renal blood flow, and decreases systemic blood pressure in response to vasoconstrictors in spontaneously hypertensive rats.
| M.Wt | 293.359 | |
| Formula | C12H11N3O2S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Rahaman MM, et al. J Biol Chem. 2015 Jul 3;290(27):16861-72.
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