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Chemical Structure : cjoc42
CAS No.: 2171519-89-2
Catalog No.: PC-47073Not For Human Use, Lab Use Only.
cjoc42 is a specific small molecule that is capable of binding to gankyrin (ITC Kd=580 nM), inhibit gankyrin activity in a dose-dependent manner.
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|---|---|---|---|
| 5 mg | $298 | In stock | |
| 10 mg | $458 | In stock | |
| 25 mg | $758 | In stock | |
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cjoc42 is a specific small molecule that is capable of binding to gankyrin (ITC Kd=580 nM), inhibit gankyrin activity in a dose-dependent manner.
cjoc42 prevents the decrease in p53 protein levels normally associated with high amounts of gankyrin, and restores p53-dependent transcription and sensitivity to DNA damage.
| M.Wt | 415.464 | |
| Formula | C20H21N3O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Methyl 4-(4-(3-(tosyloxy)propyl)-1H-1,2,3-triazol-1-yl)benzoate |
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1. Anasuya Chattopadhyay, et al. Sci Rep. 2016 Apr 5;6:23732.
2. D'Souza AM, et al. Front Pharmacol. 2021 Mar 4;12:580722.
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