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Chemical Structure : dCBP-1
CAS No.: 2484739-25-3
Catalog No.: PC-38019Not For Human Use, Lab Use Only.
dCBP-1 is a potent, selective chemical degrader of p300/CBP based on PROTAC.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $228 | In stock | |
| 10 mg | $358 | In stock | |
| 25 mg | $558 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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dCBP-1 is a potent, selective chemical degrader of p300/CBP based on PROTAC.
dCBP-1 induces degradation of large proteins, including BCR-ABL and SMARCA2/4.
dCBP-1 also decreases IKZF1 and IKZF3 levels by direct degradation or transcription effects.
dCBP-1 induces near-complete p300/CBP degradation across other multiple myeloma cell lines.
dCBP-1 is a high-quality selective chemical inhibitor of p300/CBP function.
| M.Wt | 1028.13 | |
| Formula | C51H63F2N11O10 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1Hpyrazol-4-yl)-1(2H)-quinolinyl]-1-[1-[15-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]-1-oxo-4,7,10,13-tetraoxapentadec-1-yl]-4-piperidinyl]-1,4,6,7-tetrahydro-N-methyl- |
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1. Vannam R, et al. Cell Chem Biol. 2021 Apr 15;28(4):503-514.e12.
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