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miR544-IN-1

Chemical Structure : miR544-IN-1

CAS No.: 522606-67-3

miR544-IN-1 (SID 3712249)

Catalog No.: PC-62390Not For Human Use, Lab Use Only.

miR544-IN-1 (SID 3712249) is a selective small molecule inhibitor of miR-544 biogenesis.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

miR544-IN-1 (SID 3712249) is a selective small molecule inhibitor of miR-544 biogenesis; selectively inhibits production of the mature microRNA, sensitizes cells to 5-fluorouracil, and derepresses mRNAs affected by miR-544 in cellulo and in vivo, including boosting mTOR expression; reverses a tumor cell's physiological response to hypoxia.

Physicochemical Properties

M.Wt 323.404
Formula C17H21N7
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1,8-diamino-3,6-di(pyrrolidin-1-yl)-2,7-naphthyridine-4-carbonitrile

References

1. Haga CL, et al. ACS Chem Biol. 2015 Oct 16;10(10):2267-76.

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