| Cat. No. |
Product Name |
Information |
| PC-43433 |
A-674563
Akt inhibitor
|
A-674563 is a potent, selective and orally available AKT inhibitor with Ki of 11 nM (Akt1). |
| PC-43370 |
Isobavachalcone
Akt inhibitor
|
Isobavachalcone (Corylifolinin, Isobacachalcone) is a chalcone constituent of Angelica keiskei that can induce apoptosis in several cancer cells, is a potent inhibitor of Akt signaling pathway. |
| PC-42878 |
PHT-427
Akt inhibitor
|
PHT-427 (PHT427) is a small-molecule Akt inhibitor that binds selectively to the PH domain of AKT with Ki of 2.4 uM, inhibits phospho-Ser473-AKT in Panc-1 cells with IC50 of 6.3 uM. |
| PC-42874 |
AT7867 dihydrochloride
p70S6K/Akt inhibitor
|
AT7867 dihydrochloride is a potent, ATP-competitive, orally available dual Akt and p70S6K inhibitor with Ki of 17-85 nM, also inhibits PKA with Ki of 20 nM. |
| PC-42873 |
AT7867
p70S6K/Akt inhibitor
|
AT7867 (AT-7867) is a potent, ATP-competitive, orally available dual Akt and p70S6K inhibitor with Ki of 17-85 nM, also inhibits PKA with Ki of 20 nM. |
| PC-62833 |
TAS-117
Akt inhibitor
|
TAS-117 is a highly selective, non-ATP competitive pan-Akt inhibitor with IC50 of 4.8/1.6/44 nM for Akt1/Akt2/Akt3 respectively. |
| PC-62208 |
10-NCP
Akt inhibitor
|
10-NCP (10-DEBC) is a potent neuronal autophagy inducer and increases TDP43 clearance, a reversible and specific inhibitor of Akt activity in vitro (complete inhibition at < 5 uM). |
| PC-61416 |
LY2780301
p70S6K/Akt inhibitor
|
LY2780301 is a potent, highly selective, ATP-competitive dual inhibitor of p70S6K and Akt under development for the treatment of solid tumours and non-Hodgkin's lymphoma. |
| PC-70086 |
BI-69A11
Akt inhibitor
|
BI-69A11 is a potent, selective, ATP competitive AKT inhibitor with IC50 of 2.3 uM for Akt1. |
| PC-45738 |
SC-66
Akt inhibitor
|
SC66 is an allosteric Akt inhibitor, exhibits a dual inhibitory activity that directly interferes with the PH domain binding to PIP3 and facilitates Akt ubiquitination. |
| PC-42485 |
TCMDC-136364
Akt inhibitor
|
TCMDC-136364 (AKT Kinase Inhibitor) is an Akt kinase inhibitor, selectively inhibits Akt in proliferating cells expressing Trop-2, also potently inhibits P. falciparum multidrug resistant strain Dd2. |
| PC-45548 |
SC-79
Akt activator
|
SC-79 is a unique specific Akt activator, binds to the PH domain of Akt and inhibits Akt membrane translocation, but paradoxically activates Akt in the cytosol. |
