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Cat. No. Product Name Information
PC-43433

A-674563

Akt inhibitor

A-674563 is a potent, selective and orally available AKT inhibitor with Ki of 11 nM (Akt1).
PC-43370

Isobavachalcone

Akt inhibitor

Isobavachalcone (Corylifolinin, Isobacachalcone) is a chalcone constituent of Angelica keiskei that can induce apoptosis in several cancer cells, is a potent inhibitor of Akt signaling pathway.
PC-42878

PHT-427

Akt inhibitor

PHT-427 (PHT427) is a small-molecule Akt inhibitor that binds selectively to the PH domain of AKT with Ki of 2.4 uM, inhibits phospho-Ser473-AKT in Panc-1 cells with IC50 of 6.3 uM.
PC-42874

AT7867 dihydrochloride

p70S6K/Akt inhibitor

AT7867 dihydrochloride is a potent, ATP-competitive, orally available dual Akt and p70S6K inhibitor with Ki of 17-85 nM, also inhibits PKA with Ki of 20 nM.
PC-42873

AT7867

p70S6K/Akt inhibitor

AT7867 (AT-7867) is a potent, ATP-competitive, orally available dual Akt and p70S6K inhibitor with Ki of 17-85 nM, also inhibits PKA with Ki of 20 nM.
PC-62833

TAS-117

Akt inhibitor

TAS-117 is a highly selective, non-ATP competitive pan-Akt inhibitor with IC50 of 4.8/1.6/44 nM for Akt1/Akt2/Akt3 respectively.
PC-62208

10-NCP

Akt inhibitor

10-NCP (10-DEBC) is a potent neuronal autophagy inducer and increases TDP43 clearance, a reversible and specific inhibitor of Akt activity in vitro (complete inhibition at < 5 uM).
PC-61416

LY2780301

p70S6K/Akt inhibitor

LY2780301 is a potent, highly selective, ATP-competitive dual inhibitor of p70S6K and Akt under development for the treatment of solid tumours and non-Hodgkin's lymphoma.
PC-70086

BI-69A11

Akt inhibitor

BI-69A11 is a potent, selective, ATP competitive AKT inhibitor with IC50 of 2.3 uM for Akt1.
PC-45738

SC-66

Akt inhibitor

SC66 is an allosteric Akt inhibitor, exhibits a dual inhibitory activity that directly interferes with the PH domain binding to PIP3 and facilitates Akt ubiquitination.
PC-42485

TCMDC-136364

Akt inhibitor

TCMDC-136364 (AKT Kinase Inhibitor) is an Akt kinase inhibitor, selectively inhibits Akt in proliferating cells expressing Trop-2, also potently inhibits P. falciparum multidrug resistant strain Dd2.
PC-45548

SC-79

Akt activator

SC-79 is a unique specific Akt activator, binds to the PH domain of Akt and inhibits Akt membrane translocation, but paradoxically activates Akt in the cytosol.

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