You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Cathepsin

Request The Product List ofCathepsin Cathepsin

Cat. No. Product Name Information
PC-49223

MK-1256

Cathepsin K inhibitor

MK-1256 (MK1256) is a potent, selective cathepsin K (Cat K) inhibitor with IC50 of 0.62 nM, >1100-fold selectivity over Cat B, L, S, C, H, Z, and V, 110-fold over Cat F.
PC-73032

K777

Cathepsin L inhibitor

K777 (K11777, S-001, SLV213) is a highly potent, irreversible, covalent inhibitor of mammalian cathepsin L and other cysteine proteases of clan CA.
PC-38309

Z-Arg-Lys-AOMK

Cathepsin B inhibitor

Z-Arg-Lys-AOMK is a potent, selective, irreversible neutral pH 7.2 inhibitor of Cathepsin B with IC50 of 13 nM, >100-fold higher potent than at pH 4.6 (IC50=1,830 nM).
PC-38292

BI-1915

Cathepsin S inhibitor

BI-1915 (BI 1915) is a highly potent, selective inhibitor of Cathepsin S (CatS) with IC50 of 17 nM for in vitro use, no significant inhibition on Cathepsin L/K/B (IC50>10 uM).
PC-38291

BI-1124

Cathepsin S inhibitor

BI-1124 (BI 1124) is a highly potent, selective inhibitor of Cathepsin S (CatS) with IC50 of 7 nM, >40-fold selectivity over Cathepsin L/K/B.
PC-35163

MIV-711

Cathepsin K inhibitor

MIV-711 (MIV711, MV076159) is a potent, selective cathepsin K inhibitor with Ki of 0.98 nM, displays >1300-fold versus the other human cathepsins.
PC-35082

Cathepsin B inhibitor RC1

Cathepsin B inhibitor

Cathepsin B inhibitor RC1 is a small-molecule that blocks the process of anthrax lethal toxin (LT) cytotoxicity, inhibits enzymatic activity of host cathepsin B that mediates the escape of toxins into the cytoplasm from late endosomes.
PC-62965

VEL-0230

Cathepsin inhibitor

VEL-0230 (NC-2300) is a potent, selective cysteine Cathepsins inhibitor with IC50 of 284, 34.5 and 186 nM for Cat B, K and S, respectively.
PC-62964

L 873724

Cathepsin K inhibitor

L 873724 is a potent and selective non-basic cathepsin K inhibitor with IC50 of 0.2 nM, shows no significant potency against Cat B, L, and S (IC50= 5239, 264, and 178 nM).
PC-62962

Relacatib

Cathepsin K inhibitor

Relacatib (SB-462795, GSK-462795) is a potent and orally bioavailable small molecule cathepsin inhibitor with Ki of 41, 68 and 53 pM for cathepsin K, L and V, respectively.
PC-62961

MK-0674

Cathepsin K inhibitor

MK-0674 (MK 0674) is a potent, selective, reversible and orally active cathepsin K inhibitor with IC50 of 1 nM.
PC-62813

KGP-94

Cathepsin L inhibitor

KGP-94 is a potent, selective cathepsin L inhibitor with IC50 of 189 nM, shows no significant inhibitory effect on cathepsin B (IC50>10 uM).

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com