| Cat. No. |
Product Name |
Information |
| PC-45364 |
Satraplatin
|
Satraplatin (BMS-182751, BMY-45594, JM-216) is a platinum-based antineoplastic agent that binds to guanine residues in DNA, inhibits DNA replication and transcription, leads to subsequent apoptosis. |
| PC-45240 |
Ifosfamide
|
A nitrogen mustard alkylating agent used in the treatment of cancer.. |
| PC-45909 |
Trabectedin
|
Trabectedin (Ecteinascidin-743, ET-743, Ecteinascidin) is a marine alkaloid isolated from the Caribbean tunicate Ecteinascidia turbinata that shows remarkably anticancer activity in a variety of in vitro and in vivo systems. |
| PC-45216 |
Cisplatin
|
A chemotherapy agent that interferes with DNA replication and kills cancer cells. |
| PC-45215 |
Carboplatin
|
A chemotherapy agent that interferes with DNA replication and kills cancer cells. |
| PC-45363 |
Melphalan
|
A chemotherapy agent that acts through alkylation of the DNA nucleotide guanine, and causes linkages between strands of DNA. |
| PC-21822 |
QN-302
G-quadruplex binder
|
QN-302 (SOP1812) is a tetrasubstituted naphthalene diimide compound binding to G-quadruplex (G4) DNA structures, shows high potency in pancreatic ductal adenocarcinoma (PDAC) cells. |
| PC-21025 |
CDEAH
|
CDEAH is a monofunctional alkylating agent that selectively kills PARP1- and xeroderma pigmentosum A-deficient cells. |
| PC-20967 |
VAL-083
Alkylating agent
|
VAL-083 (Dianhydrodulcitol) is a small alkylating molecule that induces interstrand DNA crosslinking, induces persistent DNA double-strand breaks (DSB) and cell-cycle arrest in a p53-dependent or p53-independent manner. |
| PC-43488 |
Mitomycin C
|
Mitomycin C (Ametycine) is a chemotherapeutic antibiotic that acts as a double-stranded DNA alkylating agent.. |
| PC-63051 |
Dicycloplatin
|
Dicycloplatin (DCP) is a novel platinum analog that demonstrates significant antitumor activity against a variety of human cancer cell lines with IC50 of 25-30 nM. |
| PC-62506 |
CM03
|
CM03 is a G-quadruplex-binding compound that potently inhibits cell growth in PDAC cell lines (MIA PaCa-2 IC50=19 nM). |
