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Cat. No. Product Name CAS No. Information
PC-70130

MMV-667492

380877-02-1 A nove potent Ezrin inhibitor with Kd of 29.4 nM; exhibits potent anti-ezrin activity in all biologic assays and has better physicochemical properties for drug-likeness than NSC305787; a novel antimetastatic agent for the treatment of metastatic osteosarcoma.
PC-45561

NSC-305787 hydrochloride

53868-26-1 A small molecule inhibitor of Ezrin with Kd of 5.85 uM; inhibits ezrin phosphorylation, ezrin-actin interaction and ezrin-mediated motility of osteosarcoma (OS) cells in culture; inhibits lung metastasis of ezrin-sensitive cells in mice; also inhibits SHIP-1 and SHIP-2.
PC-45560

NSC-305787

785718-37-8 A small molecule inhibitor of Ezrin with Kd of 5.85 uM; inhibits ezrin phosphorylation, ezrin-actin interaction and ezrin-mediated motility of osteosarcoma (OS) cells in culture; inhibits lung metastasis of ezrin-sensitive cells in mice; also inhibits SHIP-1 and SHIP-2.

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