| Cat. No. |
Product Name |
Information |
| PC-45366 |
Micafungin sodium
Antifungal
|
Micafungin sodium (FK463) is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase, inhibits the production of 1,3-β-D-glucan in fungal cell walls, acts as a neddylation inhibitor that targets Ubiquitin-conjugating enzyme 2M (UBE2M). |
| PC-42761 |
AN-2690
LeuRS inhibitor
|
AN-2690 (Tavaborole) is an antifungal compound that inhibits cytoplasmic leucyl-tRNA synthetase (LeuRS) for the potential treatment of nnychomycosis. |
| PC-42727 |
Clotrimazole
Antifungal, UGT2B4 inhibitor
|
Clotrimazole is an antifungal agent that works by altering the permeability of the fungal cell wall, also is a selective inhibitor of UGT2B4. |
| PC-42221 |
Fosfluconazole
Antifungal
|
Fosfluconazole is a water-soluble, phosphate prodrug of fluconazole, a triazole antifungal agent and 14-alpha demethylase inhibitor used in the treatment and prevention of superficial and systemic fungal infections. |
| PC-45196 |
Posaconazole hydrate
Antifungal
|
Posaconazole hydrate is a triazole antifungal agent that blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase and accumulation of methylated sterol precursors, more potent at inhibiting 14α-demethylase than itraconazole. |
| PC-45195 |
Posaconazole
Antifungal
|
Posaconazole is a triazole antifungal agent that blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase and accumulation of methylated sterol precursors, more potent at inhibiting 14α-demethylase than itraconazole. |
| PC-45319 |
Itraconazole
Hedgehog inhibitor, C1GALT1 inhibitor
|
Itraconazole (R51211) is a triazole antifungal agent for fungal infections via inhibition of lanosterol 14α-demethylase, inhibits hedgehog signaling pathway with IC50 of 800 nM. |
| PC-45219 |
Butenafine hydrochloride
Antifungal
|
A synthetic benzylamine antifungal that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase. |
| PC-45218 |
Terbinafine
Antifungal
|
Terbinafine (TDT067) is a synthetic antifungal agent that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase. |
| PC-45365 |
Pneumocandin B0
Antifungal
|
Pneumocandin B0 (L-688786) is a strong antifungal and inhibits the synthesis of 3-beta-D-glucan synthase, which is a fundamental component in most cell walls. |
| PC-45370 |
Griseofulvin
Antifungal
|
Griseofulvin is a spirocyclic fungal natural product used in treatment of fungal dermatophytes. |
| PC-45231 |
Nystatin
Antifungal
|
Nystatin (Mycostatin) is a polyene antifungal antibiotic that works by disrupting the cell membrane of the fungal cells. |
