| Cat. No. |
Product Name |
Information |
| PC-25108 |
Cyclotriazadisulfonamide
Sec61 inhibitor
|
Cyclotriazadisulfonamide (CADA) is a specific CD4-targeted HIV entry inhibitor, inhibits the co-translational translocation of human CD4 (huCD4) into the ER lumen in a signal peptide (SP)-dependent, also is a Sec61 translocon inhibitor. |
| PC-25061 |
Lepetegravir
HIV-1 integrase inhibitor
|
Lepetegravir is a potent HIV-1 integrase inhibitor, inhibits the replication of HIV-I (IIIB) in MT-4 cells. |
| PC-25032 |
Asuptegravir
HIV-1 integrase inhibitor
|
Asuptegravir is a potent, selective HIV integrase inhibitor. |
| PC-25019 |
Suricapavir
HIV-1 integrase inhibitor
|
Suricapavir is a potent, selective HIV-1 integrase inhibitor. |
| PC-24934 |
MK-8527
HIV-1 RT inhibitor
|
MK-8527 is a potent, long-acting and orally active HIV inhibitor and nucleoside reverse transcriptase translocation inhibitor (NRTTI). |
| PC-24825 |
BIT225
HIV-1 Vpu inhibitor
|
BIT225 (BIT-225) is a specific small molecule inhibitor of HIV-1 Vpu ion channel activity, inhibits the release of HIV-1 in human MDM with EC50 of 2.25 uM. |
| PC-24720 |
NNRTI compound 5i3
NNRTI
|
NNRTI compound 5i3 is a highly potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI), shows potent antiviral activity against NNRTI-resistant strains (GH9, p1579, p5375, p1833, and p5735) with EC50 of 2.6-18.3 nM. |
| PC-24427 |
ZK-316
NNRTI
|
ZK-316 is a potent, HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) with IC50 of 0.21 uM (WT HIV-1 RT), exhibits potent and broad-spectrum activity against wild-type and clinically observed mutant strains with EC50 of 0.99-75.1 nM. |
| PC-24020 |
RDS1759
HIV-1 RNase H inhibitor
|
RDS1759 is a specific small molecule inhibitor of HIV-1 RT-associated RNase H activity with IC50 of 8.6 uM (mutated HIV-1 RT R448A), inhibits viral inhibition rate with IC50 of 0.17 uM. |
| PC-23799 |
HIV-1 nuclear import inhibitor H27
HIV-1 nuclear import inhibitor
|
HIV-1 nuclear import inhibitor H27 is a specific HIV-1 capsid-targeting inhibitor that specifically blocks HIV-1 nuclear import, inhibits HIV-1 infection with IC50 of 1.0-2.9 µM in HeLa-R5 and 2.9-5.6 µM in primary lymphocytes. |
| PC-23743 |
Elvitegravir
NNRTI
|
Elvitegravir (JTK-303, GS-9137) is a potent, selective HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) with IC50 of 7.2 nM in 7.2 nM in the strand transfer assay and EC50 of 0.9 nM in acute HIV-1 infection assay. |
| PC-23582 |
Dapivirine
NNRTI
|
Dapivirine (TMC120, R147681) is a potent, HIV-1 nonnucleoside reverse transcriptase inhibitor (NNRTI) with IC50 of 24 nM, inhibits syncytium formation of HIV-1 IIIB-infected CEM T cells with EC50 of 1 nM, shows high activity against wild-type and mutant HIV. |
