| Cat. No. |
Product Name |
Information |
| PC-45052 |
Remodelin hydrobromide
NAT10 inhibitor
|
Remodelin hydrobromide is a potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules. |
| PC-45051 |
Remodelin
NAT10 inhibitor
|
Remodelin is a potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules. |
| PC-25583 |
Anacardic acid
HAT inhibitor
|
Anacardic acid is a small molecule inhibitor of histone acetyltransferase (HAT) with IC50 of 8.5 and 5.0 uM for p300 and PCAF respectively. |
| PC-25107 |
KI-TOX-A3
TOX-KAT7 inhibitor
|
KI-TOX-A3 is a specific TOX protein (thymocyte selection-associated high mobility group box) binder (KD=0.92 uM) and potent TOX-KAT7 PPI inhibitor with IC50 of 0.51 uM. |
| PC-24370 |
Curcumin
p300 inhibitor
|
Curcumin (Diferuloylmethane) is a specific p300/CREB-binding protein acetyltransferase, inhibits acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. |
| PC-24309 |
LFW273
Snail inhibitor
|
LFW273 is a specific, orally bioavailable small molecule inhibitor of zinc-finger transcription factor Snail with binding Kd of 1.7 uM, inhibits CREB-binding protein (CBP)-Snail interaction with Kd of 7.3 uM in MST assays. |
| PC-24033 |
EPS496
p300 inhibitor
|
EPS496 is a small molecule inhibitor of histone acetyltransferase p300, binds effectively to p300 and inhibits p300 kinase activation. |
| PC-23724 |
CHI-KAT8i5
KAT8 inhibitor
|
CHI-KAT8i5 is a specific small molecule inhibitor of KAT8 (lysine acetyltransferase 8), directly binds to KAT8 with SPR KD of 19.72 uM, suppresses esophageal squamous cell carcinoma (ESCC) growth through targeting KAT8/c-Myc signaling pathway. |
| PC-21986 |
EPIC-0628
HOTAIR-EZH2 inhibitor
|
EPIC-0628 (EPIC0628) is a selective and potent inhibitor that selectively disrupts the HOTAIR-EZH2 interaction and promotes ATF3 expression, enhances the temozolomide efficacy in glioblastoma. |
| PC-21843 |
SGF29 inhibitor DC60
SGF29 inhibitor
|
SGF29 inhibitor DC60 is a small molecule inhibitor of Spt-Ada-Gcn5 acetyltransferase (SAGA)-associated factor 29 (SGF29, CCDC101) with IC50 of 6.4 uM, binds to SGF29 second Tudor domain (SGF29 Tudor 2) and blocks SGF29 chromatin binding domain. |
| PC-20867 |
MG149
Tip60 (KAT5) inhibitor
|
MG149 is a selective histone acetyltransferase Tip60 (KAT5) inhibitor with IC50 of 74 uM, with no activity against PCAF and p300. |
