| Cat. No. |
Product Name |
Information |
| PC-60028 |
A-485
p300/CBP inhibitor
|
A-485 (A485) is a potent, selective and, cell and in vivo active p300/CBP catalytic inhibitor with IC50 of 9.8/2.6 nM. |
| PC-45646 |
I-CBP112
CBP/p300 inhibitor
|
I-CBP112 is a specific and potent inhibitor of CBP/p300 bromodomain with Kd of 150-170 nM. |
| PC-45052 |
Remodelin hydrobromide
NAT10 inhibitor
|
Remodelin hydrobromide is a potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules. |
| PC-45051 |
Remodelin
NAT10 inhibitor
|
Remodelin is a potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules. |
| PC-27595 |
CBP/p300 ligand 2
CBP/p300 ligand
|
CBP/p300 ligand 2 is a high affinity ligand of CBP/p300 for PROTAC design. |
| PC-27555 |
CTX-0124143
KAT6A inhibitor
|
CTX-0124143 is a small molecule inhibitor of Monocytic leukemia zinc finger protein (MOZ/KAT6A) with IC50 of 1.0 uM. |
| PC-27554 |
MOZ-IN-3
KAT6A inhibitor
|
MOZ-IN-3 (KAT6A inhibitor 6j) is a potent, selective inhibitor of KAT6A (MOZ, Monocytic leukemia zinc finger protein) with IC50 of 0.03 uM, shows 25-333 fold selectivity against KAT7, KAT5, KAT8 and KAT6B, exhibitsstrong antitumor activity on leukemia cell line K562 (IC50=82 nM). |
| PC-26970 |
Butyrolactone 3
GCN5 inhibitor
|
Butyrolactone 3 (MB-3) is a specific, cell-permeable small-molecule inhibitor of histone acetyltransferase GCN5 with IC50 of 100 uM. |
| PC-25583 |
Anacardic acid
HAT inhibitor
|
Anacardic acid is a small molecule inhibitor of histone acetyltransferase (HAT) with IC50 of 8.5 and 5.0 uM for p300 and PCAF respectively. |
| PC-25107 |
KI-TOX-A3
TOX-KAT7 inhibitor
|
KI-TOX-A3 is a specific TOX protein (thymocyte selection-associated high mobility group box) binder (KD=0.92 uM) and potent TOX-KAT7 PPI inhibitor with IC50 of 0.51 uM. |
| PC-24309 |
LFW273
Snail inhibitor
|
LFW273 is a specific, orally bioavailable small molecule inhibitor of zinc-finger transcription factor Snail with binding Kd of 1.7 uM, inhibits CREB-binding protein (CBP)-Snail interaction with Kd of 7.3 uM in MST assays. |
| PC-24033 |
EPS496
p300 inhibitor
|
EPS496 is a small molecule inhibitor of histone acetyltransferase p300, binds effectively to p300 and inhibits p300 kinase activation. |
