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Cat. No. Product Name Information
PC-22264

HG-10-102-01

LRRK2 inhibitor

HG-10-102-01 is a potent and selective inhibitor of wild-type LRRK2 and LRRK2 G2019S mutant with IC50 of 20.3 nM and 3.2 nM, respectively.
PC-21271

MK-1468

LRRK2 inhibitor

MK-1468 is a potent, selective, brain-penetrant LRRK2 inhibitor with IC50 of 0.4 nM (G2019S LRRK2), potently inhibits the phosphorylation of LRRK2 serine 935 (pSer935) in hPBMCs with IC50 of 2.8 nM.
PC-49820

BIIB122

LRRK2 inhibitor

BIIB122 (DNL151) is a potent, selective, CNS-penetrant LRRK2 inhibitor.

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