| PC-28026 |
Ampyrone
Tyrosinase agonist
|
Ampyrone (4-Aminoantipyrine) is a nonsteroidal antiinflammatory drug, PGE2-dependent blocker and inhibitor of cyclooxygenase (COX), also is a direct agonist of human Tyrosinase (TYR), increases catalytic activity of both hTYRWT and hTYRP406L with EC50 of 0.67 and 3.57 mM, respectively. |