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5J89LIG

Chemical Structure : 5J89LIG

CAS No.: 1675203-84-5

5J89LIG

Catalog No.: PC-49099Not For Human Use, Lab Use Only.

5J89LIG is a small molecule h-PD1/h-PD-L1 interaction inhibitor with IC50 of 18.0 nM, bind specifically to hPD-L1 through a unique mode of action, induces the dimerization of hPD-L1.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

5J89LIG is a small molecule h-PD1/h-PD-L1 interaction inhibitor with IC50 of 18.0 nM, bind specifically to hPD-L1 through a unique mode of action, induces the dimerization of hPD-L1.

Physicochemical Properties

M.Wt 419.525
Formula C25H29N3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-(((2-methoxy-6-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)pyridin-3-yl)methyl)amino)ethyl)acetamide

References

1. Zak KM, et al. Oncotarget. 2016;7(21):30323–30335.

2. Marawan Ahmed, et al. BMC Chem. 2022 Jun 27;16(1):49.

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