| Cat. No. |
Product Name |
Information |
| PC-38688 |
Zaloglanstat
|
Zaloglanstat (ISC-27864, GRC-27864) is a potent, selective, non-opioid and orally active microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor, exhibits significant analgesic efficacy in preclinical models for osteoarthritis and inflammatory arthritis. |
| PC-36096 |
Pizuglanstat
|
TAS-205 (Pizuglanstat, TAS205) is a potent, specific hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with IC50 of 55.8 nM, does not inhibit LPGDS at 100 uM. |
| PC-36090 |
Crisdesalazine
|
Crisdesalazine (AAD-2004, AAD2004) is a derivative of aspirin that inhibits microsomal PGE(2) synthase-1 (mPGES-1) activity in response to both LPS-treated BV2 cell with IC50 of 230 nM and recombinant human mPGES-1 protein with IC50 of 249 nM in vitro. |
| PC-45791 |
Benzydamine hydrochloride
|
Benzydamine hydrochloride is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties for pain relief and anti-inflammatory treatment of inflammatory conditions. |
| PC-20721 |
PF-4693627
|
PF-4693627 is a potent, selective and orally bioavailable mPGES-1 inhibitor with IC50 of 3 nM. |
| PC-20720 |
UT-11
|
UT-11 is a potent microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor, inhibits PGE2 production from human SK-N-AS and murine BV2 cells induced by LPS with IC50 of 0.1 and 2.0 uM, respectively. |
| PC-20005 |
mPGES-1 inhibitor UK-4b
|
mPGES-1 inhibitor UK-4b is a potent, hgihly selective and orally bioavailable inhibitor of human and mouse mPGES-1 enzymes with IC50 of 33 and 157 nM, respectively, effectively decreases carrageenan-stimulated PGE2 over-production. |
