| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-38689 |
LY3023703
|
1415089-24-5 |
LY3023703 is a potent, highly selective microsomal prostaglandin E synthase 1 (mPGES1) inhibitor, dose-dependently inhibits PGE2 production in human whole blood ex vivo. |
| PC-38688 |
Zaloglanstat
|
1513852-12-4 |
Zaloglanstat (ISC-27864, GRC-27864) is a potent, selective, non-opioid and orally active microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor, exhibits significant analgesic efficacy in preclinical models for osteoarthritis and inflammatory arthritis. |
| PC-38642 |
SZ0232
|
924851-91-2 |
SZ0232 is a small molecule mPGES-2 (microsomal prostaglandin E synthase-2) inhibitor with IC50 of <1 uM, exhibits beneficial effects on modulating β-cell function and glucose metabolism both in vitro and in vivo. |
| PC-38615 |
CAY 10526
|
938069-71-7 |
CAY10526 is an inhibitor of PGE2 production through the selective modulation of mPGES-1 expression, dose-dependently inhibits PGE2 production in LPS-stimulated RAW 264.7 cells with IC50 of 1.8 uM. |
| PC-38455 |
AT-56
|
162640-98-4 |
AT-56 is an orally active, selective inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS) with Ki of 75 uM, IC50 of 95 uM. |
| PC-36096 |
Pizuglanstat
|
1244967-98-3 |
Pizuglanstat is a potent, selective prostaglandin D synthase inhibitor.. |
| PC-36090 |
Crisdesalazine
|
927685-43-6 |
Crisdesalazine (AAD-2004, AAD2004) is a derivative of aspirin that inhibits microsomal PGE(2) synthase-1 (mPGES-1) activity in response to both LPS-treated BV2 cell with IC50 of 230 nM and recombinant human mPGES-1 protein with IC50 of 249 nM in vitro. |
