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Chemical Structure : AM1241
CAS No.: 444912-48-5
Catalog No.: PC-60729Not For Human Use, Lab Use Only.
AM1241 is a potent, selective cannabinoid receptor CB2 agonist with Ki of 7.1 nM, >80-fold selectivity over CB1 receptors in radioligand binding assay.
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|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $148 | In stock | |
| 50 mg | $238 | In stock | |
| 100 mg | Get quote |
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AM1241 is a potent, selective cannabinoid receptor CB2 agonist with Ki of 7.1 nM, >80-fold selectivity over CB1 receptors in radioligand binding assay.
AM1241 suppresses spinal fos protein expression and pain behavior in a rat model of inflammation.
AM1241 dose-dependently reversed tactile and thermal hypersensitivity produced by ligation of the L5 and L6 spinal nerves in rats.
| M.Wt | 503.3 | |
| Formula | C22H22IN3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(2-iodo-5-nitrophenyl)-(1-(1-methylpiperidin-2-ylmethyl)-1H-indol-3-yl)methanone |
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1. Malan TP Jr, et al. Pain. 2001 Sep;93(3):239-45.
2. Nackley AG, et al. Neuroscience. 2003;119(3):747-57.
3. Yao BB, et al. Br J Pharmacol. 2006 Sep;149(2):145-54.
4. Ibrahim MM, et al. Proc Natl Acad Sci U S A. 2003 Sep 2;100(18):10529-33.
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