Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : BBT-594
CAS No.: 882405-89-2
Catalog No.: PC-45558Not For Human Use, Lab Use Only.
BBT-594 (NVP-BBT594) is a potent RET inhibitor that can impairs GDNF-RET signaling and GDNF-dependent growth of MCF7-LTED cells.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $98 | In stock | |
| 25 mg | $188 | In stock | |
| 100 mg | $428 | In stock | |
| 500 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
BBT-594 (NVP-BBT594) is a potent RET inhibitor that can impairs GDNF-RET signaling and GDNF-dependent growth of MCF7-LTED cells; significantly enhances the antiproliferative effects of letrozole (SF50=2.9 nM).
| M.Wt | 569.5781 | |
| Formula | C28H30F3N7O3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
DMSO: ≥ 33 mg/mL |
|
| Chemical Name/SMILES |
1H-Indole-1-carboxamide, 5-[[6-(acetylamino)-4-pyrimidinyl]oxy]-2,3-dihydro-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]- |
|
1. Morandi A, et al. Cancer Res. 2013 Jun 15;73(12):3783-95.
2. Andreucci E, et al. Oncotarget. 2016 Dec 6;7(49):80543-80553.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
