Catalog No.: PC-20464Not For Human Use, Lab Use Only.
ACBI2 (BI 1810284, BI 01810284) is a potent, selective and orally bioavailable VHL-recruiting PROTAC degrader of SMARCA2 (DC50=1 nM in RKO cells), 30-fold selectivity over SMARCA4.
ACBI2 (BI 1810284, BI 01810284) is a potent, selective and orally bioavailable VHL-recruiting PROTAC degrader of SMARCA2 (DC50=1 nM in RKO cells), 30-fold selectivity over SMARCA4.
ACBI2 (80 mg/kg, oral) induces lung cancer tumour growth inhibition in A549 tumour bearing mice.
