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BM-635

Chemical Structure : BM-635

CAS No.: 1073372-01-6

BM-635 (BM635)

Catalog No.: PC-61754Not For Human Use, Lab Use Only.

BM-635 is a small molecule anti-mycobacterial compound acting by inhibiting the mycobacterial membrane protein Large 3 (MmpL3).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BM-635 is a small molecule anti-mycobacterial compound acting by inhibiting the mycobacterial membrane protein Large 3 (MmpL3); shows outstanding anti-mycobacterial activity (MIC of 0.12 uM against M. tuberculosis H37Rv).

Physicochemical Properties

M.Wt 331.223
Formula C17H26BN3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-[4-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]-1-piperazinyl]ethanone

References

1. Poce G, et al. Eur J Pharm Sci. 2017 Mar 1;99:17-23.

2. Poce G, et al. Eur J Med Chem. 2017 Dec 27;145:539-550.

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