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BQU-057

Chemical Structure : BQU-057

CAS No.: 1637739-82-2

BQU-057 (BQU057, BQU57)

Catalog No.: PC-62792Not For Human Use, Lab Use Only.

BQU-057 is a novel potent small GTPase Ral (Ras-like) inhibitor with IC50 of 2.2 uM, displays a dose dependent effect on RalA and RalB activity in H2122 spheroids using the common RalBP1 pull-down assay..

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Biological Activity

BQU-057 is a novel potent small GTPase Ral (Ras-like) inhibitor with IC50 of 2.2 uM, displays a dose dependent effect on RalA and RalB activity in H2122 spheroids using the common RalBP1 pull-down assay.

Physicochemical Properties

M.Wt 334.302
Formula C16H13F3N4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-amino-1,3-dimethyl-4-(4-(trifluoromethyl)phenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile

References

1. Yan C, et al. Bioorg Med Chem Lett. 2016 Dec 1;26(23):5815-5818.

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