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Chemical Structure : BW-723C86
Catalog No.: PC-60816Not For Human Use, Lab Use Only.
A potent, selective 5-HT2B receptor agonist with pKi of 7.1, >10-fold selectivity over 5-HT2A, 5-HT2C, and other 5-HT subtypes.
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A potent, selective 5-HT2B receptor agonist with pKi of 7.1, >10-fold selectivity over 5-HT2A, 5-HT2C, and other 5-HT subtypes; exerts an appreciable anxiolytic-like profile in a rat social interaction test, causes hyperphagia and reduced grooming in rats.
Anxiety
Preclinical
| M.Wt | 322.85 | |
| Formula | C16H18N2OS.HCl | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kennett GA, et al. Neuropharmacology. 1997 Feb;36(2):233-9.
2. Kennett GA, et al. Br J Pharmacol. 1996 Apr;117(7):1443-8.
3. Ellis ES, et al. Br J Pharmacol. 1995 Jan;114(2):400-4.
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