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Bremelanotide

Chemical Structure : Bremelanotide

CAS No.: 189691-06-3

Bremelanotide (PT-141;PT 141)

Catalog No.: PC-70138Not For Human Use, Lab Use Only.

A peptide, non-selective melanocortin receptor agonist for treatment for female sexual dysfunction.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A peptide, non-selective melanocortin receptor agonist for treatment for female sexual dysfunction; selectively stimulates solicitational behaviors in the female rat, without affecting lordosis, pacing, or other sexual behaviors, does not cause generalized motor activation; a peptide analogue of α-MSH.

Sexual Dysfunction

Phase 3 Clinical

Physicochemical Properties

M.Wt 1025.2
Formula C50H68N14O10
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-Acetyl-L-norleucyl-L-alpha-aspartyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl-L-lysine (2-7)-lactam

References

1. Pfaus JG, et al. Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):10201-4.

2. Molinoff PB, et al. Ann N Y Acad Sci. 2003 Jun;994:96-102.

3. Aughton KL, et al.

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