Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Bryostatin 1
Catalog No.: PC-35396Not For Human Use, Lab Use Only.
Bryostatin 1 (NSC 339555) is a macrocyclic lactone derived from a marine invertebrate, fuctions as an activator of PKC with high binding affinity (Ki=1.35 nM).
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Bryostatin 1 (NSC 339555) is a macrocyclic lactone derived from a marine invertebrate, fuctions as an activator of PKC with high binding affinity (Ki=1.35 nM); functions like the phorbol esters biochemically in binding to and activating protein kinase C; inhibits tumor promotion by phorbol esters in SENCAR mouse skin, induces differentiation of B-chronic lymphocytic leukemia cells; blocks phorbol ester action in Friend cells, restores the differentiation respons with EC50 of 15 nM.
Alzheimer Disease
Phase 2 Clinical
| M.Wt | 905.044 | |
| Formula | C47H68O17 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Wender PA, et al. Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6624-9.
2. Sako T, et al. Cancer Res. 1987 Oct 15;47(20):5445-50.
3. Dell'Aquila ML, et al. Cancer Res. 1987 Nov 15;47(22):6006-9.
4. Drexler HG, et al. Blood. 1989 Oct;74(5):1747-57.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
